Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Data sources include Micromedex (updated 7 Jul 2024), Cerner Multum™ (updated 14 Jul 2024), ASHP (updated 10 Jul 2024) and others. It is important to tell your doctor about all other medications you use, including vitamins and herbs.
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Limiting alcohol in general while you’re treating an infection may help you heal quicker and lower your risk of side effects. However, it should be safe to consume alcohol again about hours (between two to three days) after you finish your course of amoxicillin. Remember that the interactions mentioned above do not reflect every antibiotic that interacts with alcohol.
Why You Should Avoid Alcohol on Antibiotics
To our knowledge, there are no data available on the efficacy/toxicity or ADR of penicillins. There are several antibiotics that people should not mix alcohol with. Not only can they interfere with the way the antibiotics work, but they can also cause a number of harmful side effects. Metronidazole is a nitroimidazole antibiotic that doctors prescribe to treat abdominal infections, sexually transmitted infections, and other anaerobic bacteria-related infections. They should also avoid other foods that contain tyramine, such as strong cheeses and smoked meats.
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Amoxicillin and certain other prescription medications can also cause these side effects. While alcohol does not interact with every prescription drug, in many cases, it can worsen existing side effects or cause additional, independent side effects. Amoxicillin is sometimes used off-label to treat Lyme disease or to prevent infections during certain surgeries or dental work.
Finishing the course of antibiotic treatment prescribed for your condition is essential. This helps prevent bacteria from becoming resistant to antibiotics. Some alcohol and drug interactions can be dangerous and may result in severe symptoms. On the other hand, some antibiotics don’t interact with unequal pupils symptoms, causes, and treatment alcohol and are found to be generally safe to take, even if you drink alcohol. Mixing amoxicillin and certain other prescription medications may worsen or increase your risk of experiencing these symptoms. Just a few days of antibiotics can wipe out uncomfortable or painful illnesses or infections.
This effect with alcohol is also possible with absorption through the skin or vagina of metronidazole cream or metronidazole gel. To our knowledge, there are no data available on the efficacy of cycloserine. Cycloserine is a second-line agent in the treatment of tuberculosis and nontuberculosis mycobacterial diseases (98, 118). To our knowledge, there are no data available on the PK/PD or efficacy of ethionamide.
Isoniazid (plus rifampin) is found in other drug combinations used for TB called Rifamate or IsonaRif. First-line treatment of pulmonary tuberculosis (TB) involves an initial phase of four agents (isoniazid, pyrazinamide, ethambutol, and rifampin) (98). Multidrug-resistant tuberculosis has necessitated the use of second-line agents, which can result in adverse neurological reactions, making concomitant use with alcohol undesirable (99).
To our knowledge, there are no data available on the PK/PD or efficacy of griseofulvin. Griseofulvin is an oral antifungal approved for the treatment of various ringworm infections due to Microsporum, alcohol and dopamine does alcohol release dopamine Epidermophyton, and Trichophyton (93). To our knowledge, there are no data available on the PK/PD or efficacy of azoles. Azoles are antifungals approved for the treatment of fungal infections (88).
Combining these antibiotics and alcohol can cause a potentially dangerous reaction. Doctors recommend avoiding alcohol while taking a number of drugs. Once the women were prescribed daily doxycycline, syphilis vanished among them. Chlamydia declined by about two thirds, but this shift was only marginally statistically significant. Syphilis, which public health experts thought as recently as the 1990s could possibly be eliminated, has seen especially worrying increases among pregnant women in particular.
But if you are taking one of these medications, you probably should avoid drinking anyway as you recover from your infection. The use of alcohol with griseofulvin is not recommended by the National Consumers League, the FDA, or the NIH (4, 5). Package labeling warns that griseofulvin may potentiate the effects of alcohol, resulting in tachycardia and flushing (93). Disulfiram-like reactions have been reported in the literature (94,–96). Reactions can range in severity; one patient required admission to the intensive care unit (97).
- Further research is needed to better understand this kind of messaging to communicate the facts about antibiotic resistance and change behaviour.
- However, another global pandemic is unfolding in front of our eyes1.
- The use of alcohol with sulfonamides has been found to cause facial flushing, but otherwise, data on risk are limited.
- Antimicrobial resistance caused 1.27 million deaths and played a role in 4.95 million deaths in 2019 across the world2.
- In most cases, Dr. Clayton says you should get nonalcoholic beverages instead (mocktails, anyone?), as you shouldn’t put off starting your antibiotic.
Although data are not optimal, it is reasonable to advise avoidance of alcohol consumption in patients taking isoniazid. A disulfiram-like reaction and a possible increased risk of hepatitis are potential concerns. Early in vitro studies suggested that metronidazole or its metabolites inhibited liver alcohol dehydrogenase (67,–69).
Those that are cleared by the liver have the highest potential for serious adverse reactions with alcohol. Nitroimidazole antimicrobials are a class of antibiotics that alcohol and drug detox treatment blog stop bacterial growth. It’s also important to finish the entire course of antibiotics a doctor prescribes; stopping the drug early can lead to antibiotic resistance.
Risks are greater for people with underlying blood pressure problems who consume a lot of alcohol. There is a risk for additive liver toxicity, especially if you have preexisting liver disease or chronically abuse alcohol. Check with your doctor before you consume alcohol while taking pyrazinamide. Ketoconazole is an oral antifungal medication used to treat certain fungal infections when patients have failed other treatments or are intolerant to them and the benefits outweigh the risk. In the liver, alcohol is metabolized to acetaldehyde by the enzyme alcohol dehydrogenase. This reaction may occur due to inhibition of acetaldehyde dehydrogenase by the drug resulting in acetaldehyde accumulation and side effects.